Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863051 | 0.84 | MAOA (0.38) | KDM4ESMN1; SMN2LTA4HMAOAMAOB | |
| SCHEMBL3873466 | 0.83 | ACHE (0.46) | ACHE | |
| SCHEMBL3870674 | 0.79 | ACHE (0.44) | KDM4ESMN1; SMN2LTA4HMAOAMAOB | |
| SCHEMBL3864617 | 0.78 | PPARG (0.45) | KDM4ESMN1; SMN2CYP1A2CYP2C19TDP1 | |
| SCHEMBL5199102 | 0.76 | CYP1A2 (0.40) | KDM4ESMN1; SMN2LTA4HMAOAMAOB | |
| SCHEMBL3870282 | 0.76 | MAOA (0.40) | KDM4ESMN1; SMN2MAOAMAOBCYP1A2 | |
| SCHEMBL3863979 | 0.75 | ACHE (0.37) | TDP1ACHESLC6A4TSHRCHRNB2 | |
| SCHEMBL3867127 | 0.72 | ACHE (0.53) | SMN1; SMN2L3MBTL1ACHESLC6A4 | |
| SCHEMBL3874630 | 0.72 | KDM4E (0.47) | KDM4E | |
| SCHEMBL3870465 | 0.72 | ACHE (0.51) | KDM4ESMN1; SMN2ACHESLC6A4CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504437-B2 | Benzylamine analogues | BTG INTERNATIONAL LIMITED (GB) | 2009-03-17 | — | — | US | disclosed |