Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812418 | 0.63 | CHRNB2 (0.37) | — | |
| SCHEMBL18870955 | 0.62 | MAPT (0.39) | MAPTTDP1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2996449 | 0.61 | CHRNB2 (0.36) | — | |
| SCHEMBL2998727 | 0.61 | CHRNB2 (0.36) | — | |
| SCHEMBL2996446 | 0.61 | CHRNB2 (0.36) | — | |
| SCHEMBL2991651 | 0.61 | CHRNB2 (0.36) | — | |
| SCHEMBL943172 | 0.61 | MEN1 (0.39) | SMN1; SMN2 | |
| SCHEMBL14505996 | 0.61 | — | — | |
| SCHEMBL4628774 | 0.61 | CHRNB2 (0.36) | — | |
| SCHEMBL2998728 | 0.61 | CHRNB2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548496-B2 | Anticancer agents | AMERICAN CYANAMID COMPANY | 2003-04-15 | — | — | US | claimed |
| EP-1888567-B1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | EP | disclosed |