SCHEMBL3874015

SCHEMBL3874015

Cc1ccc(Oc2c(Oc3ccc(C)cc3)c(Oc3ccc(C)cc3)c(Oc3ccc(C)cc3)c(Oc3ccc(C)cc3)c2Oc2ccc(C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD4 Q15561 1/20 0.59
ALDH1A1 P00352 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
POLB P06746 1/20 0.56
MAPT P10636 1/20 0.56
ACHE P22303 2/20 0.55
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
GAA P10253 2/20 0.45
CYP2C9 P11712 1/20 0.45
MMP13 P45452 1/20 0.45
LMNA P02545 2/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
RELA Q04206 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95343 0.87 TEAD4 (0.74) TEAD4ALDH1A1TDP1MEN1KMT2A
SCHEMBL83814 0.87 TEAD4 (0.74) TEAD4ALDH1A1TDP1MEN1KMT2A
SCHEMBL83863 0.87 TEAD4 (0.74) TEAD4ALDH1A1TDP1MEN1KMT2A
SCHEMBL29377968 0.84 TEAD4 (0.70) TEAD4ALDH1A1TDP1MEN1KMT2A
Phosphine SCHEMBL22361928 0.84 TEAD4 (0.70) TEAD4ALDH1A1TDP1MEN1KMT2A
SCHEMBL11078772 0.83 ACHE (0.52) TEAD4ALDH1A1TDP1MEN1KMT2A
SCHEMBL31008769 0.82 HTT (0.49) TEAD4ALDH1A1TDP1MEN1KMT2A
SCHEMBL11588965 0.82 TEAD4 (0.48) TEAD4ALDH1A1TDP1MEN1KMT2A
SCHEMBL5404593 0.82 HTT (0.49) TEAD4ALDH1A1TDP1MEN1KMT2A
SCHEMBL29170633 0.81 TEAD4 (0.67) TEAD4ALDH1A1TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7585928-B2 monomers of acetylenic homo- or copolymers; cured polymers has low dielectric constant as insulating layers in microelectronic devices DOW GLOBAL TECHNOLOGIES (US) 2009-09-08 US disclosed
US-20070027278-A1 Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom DOW GLOBAL TECHNOLOGIES LLC 2007-02-01 US disclosed
WO-2005042613-A1 MULTIFUNCTIONAL MONOMERS CONTAINING BOUND MESOGENIC PORAGEN FORMING MOIETIES AND POLYARYLENE COMPOSITIONS THEREFROM DOW GLOBAL TECHNOLOGIES INC. (US) 2005-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027278-A1 Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom LRBA, CD74, BMP2 TEAD4 4221/4885ALDH1A1 2995/4885TDP1 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.