Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.65 |
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 5/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3875239 | 1.00 | SHBG (0.65) | SHBGARCYP19A1PGRNR3C2 | |
| SCHEMBL6711427 | 0.79 | SHBG (1.00) | SHBGARCYP19A1PGRNR3C2 | |
| SCHEMBL7143244 | 0.78 | SHBG (0.70) | SHBGARCYP19A1PGRNR3C2 | |
| SCHEMBL6568987 | 0.78 | SHBG (0.70) | SHBGARCYP19A1PGRNR3C2 | |
| SCHEMBL6569593 | 0.72 | SHBG (0.65) | SHBGARCYP19A1PGRNR3C2 | |
| SCHEMBL7141591 | 0.72 | SHBG (0.65) | SHBGARCYP19A1PGRNR3C2 | |
| Mibolerone SCHEMBL4362587 | 0.71 | AR (0.67) | SHBGARPGRNR3C2ALDH1A1 | |
| Mibolerone SCHEMBL565277 | 0.71 | AR (0.67) | SHBGARPGRNR3C2ALDH1A1 | |
| Mibolerone SCHEMBL14275154 | 0.71 | AR (0.67) | SHBGARPGRNR3C2ALDH1A1 | |
| Mibolerone SCHEMBL10603681 | 0.71 | AR (0.67) | SHBGARPGRNR3C2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291929-A1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | N.V. ORGANON (NL) | 2009-11-26 | — | — | US | disclosed |
| EP-1893630-B1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | ORGANON NV (NL) | 2009-09-02 | — | — | EP | disclosed |
| EP-1893630-A1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | N.V. Organon (NL) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006134167-A1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | N.V. ORGANON (NL) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291929-A1 | STEROIDS HAVING A MIXED ANDROGENIC AND PROGESTAGENIC PROFILE | NR5A1, AR, CYP17A1 | SHBG 4/4885AR 2/4885CYP19A1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.