Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | KCNA1 | Q09470 | 3/20 | 0.39 |
| ▸ | KCNAB1 | Q14722 | 3/20 | 0.39 |
| ▸ | TMPRSS2 | O15393 | 4/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590340 | 0.87 | HTR6 (0.49) | HTR6KCNA1KCNAB1PTPN1NAMPT | |
| SCHEMBL1590388 | 0.81 | HTR6 (0.73) | HTR6KCNA1KCNAB1TMPRSS2DRD2 | |
| SCHEMBL1590171 | 0.80 | HTR6 (0.50) | HTR6DRD2HTR2AHTR2CDRD3 | |
| Hydrochloric Acid SCHEMBL1590699 | 0.79 | HTR6 (0.49) | HTR6DRD2HTR2AHTR2CDRD3 | |
| SCHEMBL1591023 | 0.78 | HTR6 (0.50) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1590228 | 0.78 | HTR6 (0.52) | HTR6HTR2CLMNASMN1; SMN2MEN1 | |
| SCHEMBL1591258 | 0.75 | HTR6 (0.49) | HTR6HTR2CLMNASMN1; SMN2MEN1 | |
| SCHEMBL16634913 | 0.73 | KCNA1 (0.49) | KCNA1KCNAB1TMPRSS2PTPN2PTPN1 | |
| SCHEMBL1590132 | 0.72 | HTR6 (0.67) | HTR6DRD2HTR2AHTR2CDRD3 | |
| SCHEMBL1590451 | 0.72 | HTR6 (0.67) | HTR6DRD2HTR2AHTR2CDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116546-A1 | Substituted N-phenyl-2,3-dihydroimidazo[2,1-b]thiazole-5-sulfonamide derivatives as 5-HT6 ligands | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2009-11-11 | — | — | EP | disclosed |