Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1014018 | 0.93 | REN (0.35) | REN | |
| SCHEMBL1014019 | 0.93 | REN (0.35) | REN | |
| SCHEMBL3945819 | 0.93 | REN (0.35) | REN | |
| SCHEMBL3945822 | 0.93 | REN (0.35) | REN | |
| SCHEMBL3950609 | 0.90 | REN (0.35) | REN | |
| SCHEMBL3940945 | 0.90 | REN (0.35) | REN | |
| SCHEMBL3950614 | 0.90 | REN (0.35) | REN | |
| SCHEMBL1015530 | 0.89 | REN (0.35) | REN | |
| SCHEMBL1015531 | 0.89 | REN (0.35) | REN | |
| SCHEMBL3885241 | 0.89 | REN (0.35) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934207-B1 | SUBSTITUTED 4-PHENYL PIPERIDINES FOR USE AS RENIN INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2009-03-11 | — | — | EP | disclosed |