Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | TPMT | P51580 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10487161 | 0.98 | CA1 (0.52) | CA1CA2TSHRTP53CA12 | |
| SCHEMBL6715937 | 0.94 | RXRA (0.53) | CA1CA2TSHRTP53CA12 | |
| SCHEMBL14714654 | 0.89 | RARB (0.53) | CA1CA2TSHRTP53CA12 | |
| SCHEMBL6924039 | 0.83 | MAPT (0.50) | KMT2AALDH1A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL792181 | 0.83 | CA1 (0.54) | CA1CA2TSHRTP53CA12 | |
| SCHEMBL6467238 | 0.81 | CA1 (0.52) | CA1CA2TSHRTP53CA12 | |
| SCHEMBL5639207 | 0.81 | CA1 (0.57) | CA1CA2TSHRCA12CA7 | |
| SCHEMBL10487158 | 0.81 | HPGD (0.39) | CA1CA2TSHRCA12CA4 | |
| SCHEMBL14829371 | 0.81 | PARP10 (0.55) | CA1CA2TSHRKMT2AALDH1A1 | |
| SCHEMBL27566996 | 0.80 | SRD5A2 (0.59) | CA1CA2TSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530617-B | Branched polyethylene glycol heterobifunctional derivative, preparation method thereof and two-component bio-related substance conjugate thereof | 厦门赛诺邦格生物科技股份有限公司 | 2020-11-27 | — | — | CN | disclosed |
| CN-108530617-A | A kind of branched polyethylene glycol Heterobifunctional derivative, preparation method and its two-component bio-related substance conjugate | 厦门赛诺邦格生物科技股份有限公司 | 2018-09-14 | — | — | CN | disclosed |
| US-20140273010-A1 | ACID-CLEAVABLE AND CLICKABLE AFFINITY CAPTURE PROBE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140273010-A1 | ACID-CLEAVABLE AND CLICKABLE AFFINITY CAPTURE PROBE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-09-18 | — | — | US | disclosed |
| CN-101611005-B | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA AS | 2013-11-06 | — | — | CN | disclosed |
| CN-101193862-B | Hydroxybenzamide derivatives and their use as inhibitors of HSP90 | ASTEX THERAPEUTICS LTD | 2013-08-21 | — | — | CN | disclosed |
| US-20110223257-A1 | RELEASABLE FUSOGENIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS | ENZON PHARMACEUTICALS, INC. (US) | 2011-09-15 | — | — | US | disclosed |
| CN-102082297-A | Lithium iron phosphate power lithium ion battery electrolyte | DONGGUAN SHANSHAN BATTERY MATERIALS CO LTD | 2011-06-01 | — | — | CN | disclosed |
| CN-101611005-A | Be used as the acetophenones of the replacement of PDE4 inhibitor | LEO PHARMA AS (DK) | 2009-12-23 | — | — | CN | disclosed |
| US-7538182-B2 | Polypeptide and protein derivatives and process for their preparation | AMYLIN PHARMACEUTICALS, INC. (US) | 2009-05-26 | — | — | US | disclosed |
| EP-1453847-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2004-09-08 | — | — | EP | disclosed |
| US-20040081660-A1 | Polypeptide and protein derivatives and process for their preparation | AMYLIN PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| CN-1471525-A | Triazole derivatives and pharmaceutical compositions containing them | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-01-28 | — | — | CN | disclosed |
| US-6673347-B1 | CONJUGATED TO POLYMER VIA SCHIFF BASE, HYDRAZONE, OXIME, OR AZOMETHINE COMPOUND; DIAGNOSING TUMORS AND METASTASIS | GRYPHON THERAPEUTICS | 2004-01-06 | — | — | US | disclosed |
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-11-27 | — | — | US | disclosed |
| WO-2003050132-A1 | 6-O-ACYL KETOLIDE DERIVATIVES OF ERYTHROMYCINE USEFUL AS ANTIBACTERIALS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-06-19 | — | — | WO | disclosed |
| EP-0507950-B1 | PROCESS FOR PRODUCING DIACETALS | NEW JAPAN CHEM CO LTD (JP) | 1998-04-08 | — | — | EP | disclosed |
| EP-0243929-B1 | Polypeptide and protein derivatives and process for their preparation | OFFORD ROBIN EWART (CH) | 1995-09-27 | — | — | EP | disclosed |
| EP-0507950-A1 | PROCESS FOR PRODUCING DIACETAL | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1992-10-14 | — | — | EP | disclosed |
| EP-0243929-A2 | Polypeptide and protein derivatives and process for their preparation | Offord, Robin Ewart (CH) | 1987-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | Q6ZSR9, ACSL6, RPS4Y1 | CA1 3983/4885CA2 2652/4885TSHR 3692/4885 |
| US-20110223257-A1 | RELEASABLE FUSOGENIC LIPIDS FOR NUCLEIC ACIDS DELIVERY SYSTEMS | FUS, HNRNPUL2, HNRNPDL | CA1 3181/4885CA2 3761/4885TSHR 3293/4885 |
| US-20040081660-A1 | Polypeptide and protein derivatives and process for their preparation | INSRR, GIPR, HM13 | CA1 2817/4885CA2 3858/4885TSHR 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.