Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.38 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5167291 | 0.83 | POLB (0.44) | POLBTDP1PTGER2PTGER4FAAH | |
| SCHEMBL5168860 | 0.82 | POLB (0.45) | POLBTDP1PTGER2PTGER4FAAH | |
| Oxalic Acid SCHEMBL5165255 | 0.79 | TDP1 (0.41) | POLBTDP1PTGER2PTGER4LMNA | |
| SCHEMBL4421342 | 0.78 | TDP1 (0.47) | POLBTDP1FAAHALDH1A1LMNA | |
| Fumaric Acid SCHEMBL1363596 | 0.78 | POLB (0.43) | POLBTDP1PTGER2FAAHALDH1A1 | |
| Maleic Acid SCHEMBL4564915 | 0.78 | POLB (0.43) | POLBTDP1PTGER2FAAHALDH1A1 | |
| SCHEMBL5167288 | 0.77 | POLB (0.43) | POLBTDP1FAAHALDH1A1LMNA | |
| SCHEMBL387695 | 0.74 | HCAR2 (0.43) | POLBTDP1FAAHALDH1A1LMNA | |
| SCHEMBL6765320 | 0.71 | TDP1 (0.49) | POLBTDP1FAAHALDH1A1LMNA | |
| SCHEMBL10597817 | 0.71 | HPGD (0.64) | POLBTDP1FAAHALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101650-B2 | Method for treating a immunology-related disease | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-01-24 | — | — | US | disclosed |