Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5167291 | 0.85 | POLB (0.44) | POLBTDP1CES1FAAHALDH1A1 | |
| SCHEMBL5168860 | 0.85 | POLB (0.45) | POLBTDP1CES1FAAHALDH1A1 | |
| Oxalic Acid SCHEMBL5165255 | 0.82 | TDP1 (0.41) | POLBTDP1LMNA | |
| SCHEMBL4421342 | 0.79 | TDP1 (0.47) | POLBTDP1CES1FAAHALDH1A1 | |
| SCHEMBL387696 | 0.77 | POLB (0.40) | POLBTDP1CES1FAAHALDH1A1 | |
| SCHEMBL6832421 | 0.76 | POLB (0.41) | POLBTDP1CES1FAAHALDH1A1 | |
| SCHEMBL6832393 | 0.75 | POLB (0.43) | POLBTDP1CES1FAAHALDH1A1 | |
| Fumaric Acid SCHEMBL1363596 | 0.74 | POLB (0.43) | POLBTDP1CES1FAAHALDH1A1 | |
| Maleic Acid SCHEMBL4564915 | 0.74 | POLB (0.43) | POLBTDP1CES1FAAHALDH1A1 | |
| SCHEMBL6765320 | 0.74 | TDP1 (0.49) | POLBTDP1CES1FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1300405-B1 | AMINO ALCOHOL DERIVATIVES | SANKYO CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| EP-1300405-A1 | AMINO ALCOHOL DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-09 | — | — | EP | disclosed |