Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512043 | 0.79 | RECQL (0.40) | RECQLGAATERTTET2CA1 | |
| SCHEMBL851945 | 0.79 | RECQL (0.61) | RECQLGAATET2CA1CA2 | |
| SCHEMBL18820682 | 0.78 | RECQL (0.45) | RECQLGAATERTTET2KDM4E | |
| SCHEMBL30946960 | 0.77 | RECQL (0.39) | RECQLGAATERTTET2CA1 | |
| SCHEMBL21141435 | 0.77 | RECQL (0.39) | RECQLGAATERTTET2CA1 | |
| Hydrochloric Acid SCHEMBL919797 | 0.77 | RECQL (0.59) | RECQLGAATET2CA1CA2 | |
| SCHEMBL30046593 | 0.76 | RECQL (0.57) | RECQLGAATERTTET2CA1 | |
| SCHEMBL2198462 | 0.74 | GAA (0.63) | RECQLGAALMNA | |
| Hydrochloric Acid SCHEMBL13837362 | 0.74 | RECQL (0.55) | RECQLGAATERTTET2CA1 | |
| SCHEMBL7648548 | 0.74 | GAA (0.40) | RECQLGAATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | claimed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | claimed |
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | disclosed |