SCHEMBL2198462

SCHEMBL2198462

CCOC(=O)CNC(=O)CN

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.63
ALDH1A1 P00352 6/20 0.50
TSHR P16473 1/20 0.50
MGAM O43451 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
HPGD P15428 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CYP1A2 P05177 1/20 0.45
PPID Q08752 2/20 0.45
PPIB P23284 1/20 0.45
PPIA P62937 1/20 0.45
PPIG Q13427 1/20 0.45
SMN1; SMN2 Q16637 3/20 0.44
MAPT P10636 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
TRPA1 O75762 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL265730 0.98 GAA (0.61) GAAALDH1A1TSHRMGAMSI
Pyrimidine SCHEMBL10479184 0.85 GAA (0.49) GAAALDH1A1TSHRHPGDMEN1
SCHEMBL28757970 0.84 GAA (0.46) GAAALDH1A1TSHRHPGDMEN1
SCHEMBL12323562 0.83 GAA (0.63) GAAALDH1A1TSHRMGAMSI
SCHEMBL5184954 0.83 GAA (0.68) GAAALDH1A1TSHRMGAMSI
SCHEMBL3584747 0.83 GAA (0.68) GAAALDH1A1TSHRMGAMSI
Hydrochloric Acid SCHEMBL713839 0.82 GAA (0.44) GAAALDH1A1TSHRHPGDMEN1
SCHEMBL23714146 0.82 GAA (0.49) GAAALDH1A1TSHRMGAMSI
SCHEMBL14890530 0.82 GAA (0.61) GAAALDH1A1TSHRMGAMSI
SCHEMBL25412979 0.81 HTR2C (0.47) GAAALDH1A1LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101460198-B Thermosensitive polyphosphazene-bioactive molecule conjugate, preparation method and application thereof KOREA INST SCI & TECH 2013-08-07 CN claimed
CN-101460198-A Thermosensitive polyphosphazene-bioactive molecule conjugate, preparation method and application thereof KOREA INST SCI & TECH (KR) 2009-06-17 CN claimed
US-20060040871-A1 Bacterial transforming agent PHARMACEUTICA LIMITED (GB) 2006-02-23 US claimed
EP-1553981-A1 BACTERIAL TRANSFORMING AGENT Pharmaceutica Limited (GB) 2005-07-20 EP claimed
WO-2003101488-A1 BACTERIAL TRANSFORMING AGENT PHARMACEUTICA LIMITED (GB) 2003-12-11 WO claimed
EP-0644887-A1 PROCESS FOR THE PREPARATION OF CLAVULANIC ACID. SMITHKLINE BEECHAM PLC (GB) 1995-03-29 EP claimed
CN-1095069-A Novel process for the preparation and/or purification of clavulanic acid or pharmaceutically acceptable salts or esters thereof SMITHKLINE BEECHAM PLC (GB) 1994-11-16 CN claimed
WO-1993025557-A1 PROCESS FOR THE PREPARATION OF CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 1993-12-23 WO claimed
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3 2 PHARMA LLC (US) 2023-11-02 US disclosed
EP-3468563-B1 COMPOUNDS FOR DELIVERING GLUTATHIONE TO A TARGET AND METHODS OF MAKING AND USING THE SAME UNIV OREGON STATE (US) 2023-09-13 EP disclosed
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2023-05-23 US disclosed
EP-3998060-A1 HAIR COSMETIC Kao Corporation (JP) 2022-05-18 EP disclosed
US-11234916-B2 Hair cosmetic KAO CORPORATION (JP) 2022-02-01 US disclosed
US-20210069081-A1 HAIR COSMETIC KAO CORPORATION (JP) 2021-03-11 US disclosed
CN-1095069-A Novel process for the preparation and/or purification of clavulanic acid or pharmaceutically acceptable salts or esters thereof SMITHKLINE BEECHAM PLC (GB) 1994-11-16 CN disclosed
WO-1993025557-A1 PROCESS FOR THE PREPARATION OF CLAVULANIC ACID SMITHKLINE BEECHAM PLC (GB) 1993-12-23 WO disclosed
US-4873228-A 2-oxo-4-carboxy-pyrimidines and their use as anti-malaria and anti-cancer agents THE UNIVERSITY OF MELBOURNE (AU) 1989-10-10 US disclosed
EP-0260057-A2 2-Oxo-4-carboxy-pyrimidines THE UNIVERSITY OF MELBOURNE (AU) 1988-03-16 EP disclosed
US-4033974-A Pyridylmethyl esters of N-(phenoxyalkanoyl)peptide derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1977-07-05 US disclosed
US-3956484-A Pyridylmethyl esters of N-(phenoxyalkanoyl)peptide derivatives for therepeutic use AMERICAN HOME PRODUCTS CORPORATION (US) 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CREBBP, CREB1, EP300 GAA 1312/4885ALDH1A1 2132/4885TSHR 4563/4885
US-20060040871-A1 Bacterial transforming agent BCAT1, BCAT2, SLC11A2 GAA 1773/4885ALDH1A1 2005/4885TSHR 2413/4885
US-20210069081-A1 HAIR COSMETIC TYR, CUTA, H1-0 GAA 1978/4885ALDH1A1 494/4885TSHR 2456/4885
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof CREBBP, CREB1, EP300 GAA 1312/4885ALDH1A1 2132/4885TSHR 4563/4885
US-11234916-B2 Hair cosmetic TYR, CUTA, H1-0 GAA 1978/4885ALDH1A1 494/4885TSHR 2456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.