SCHEMBL851945

SCHEMBL851945

COC(=O)CNC(=O)CN

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.61
TET2 Q6N021 1/20 0.52
KDM4E B2RXH2 2/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 5/20 0.44
MGAM O43451 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
TSHR P16473 4/20 0.42
HSD17B10 Q99714 3/20 0.41
EPHX2 P34913 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
GLA P06280 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL919797 0.98 RECQL (0.59) RECQLTET2KDM4ELMNAGAA
SCHEMBL30046593 0.96 RECQL (0.57) RECQLTET2KDM4ELMNAGAA
Hydrochloric Acid SCHEMBL13837362 0.94 RECQL (0.55) RECQLTET2KDM4ELMNAGAA
SCHEMBL18820682 0.85 RECQL (0.45) RECQLTET2KDM4ELMNAGAA
SCHEMBL18753028 0.82 RECQL (0.69) RECQLTET2KDM4ELMNAGAA
SCHEMBL9512043 0.81 RECQL (0.40) RECQLTET2KDM4ELMNAGAA
SCHEMBL2414615 0.81 RECQL (0.61) RECQLTET2KDM4EGAAMGAM
SCHEMBL2558596 0.80 RECQL (0.41) RECQLTET2GAACA12CA2
SCHEMBL2198462 0.80 GAA (0.63) RECQLLMNAGAAMGAMSI
SCHEMBL18913048 0.80 LMNA (0.46) RECQLTET2KDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120037719-A High-precision wear-resistant filter material coated with nano coating and preparation method thereof 江苏奥凯环境技术有限公司 2025-05-27 CN claimed
CN-107056673-A 3, 4-diaryl maleimide derivative and preparation method and application thereof 南京工业大学 2017-08-18 CN claimed
CN-120037719-B High-precision wear-resistant filter material coated with nano coating and preparation method thereof 江苏奥凯环境技术有限公司 2025-11-07 CN disclosed
CN-120037719-A High-precision wear-resistant filter material coated with nano coating and preparation method thereof 江苏奥凯环境技术有限公司 2025-05-27 CN disclosed
CN-120037719-A High-precision wear-resistant filter material coated with nano coating and preparation method thereof 江苏奥凯环境技术有限公司 2025-05-27 CN disclosed
CN-119823106-A Enhanced nucleic acid polymerization by aromatic compounds 豪夫迈·罗氏有限公司 2025-04-15 CN disclosed
CN-114144520-B Enhanced nucleic acid polymerization by aromatic compounds 豪夫迈·罗氏有限公司 2024-12-13 CN disclosed
US-20240399776-A1 COLOR DEVELOPER, THERMAL RECORDING MATERIAL, AND THERMAL RECORDING LAYER COATING MATERIAL SANKO CO., LTD. (JP) 2024-12-05 US disclosed
CN-118450907-A Antibody drug conjugates 百济神州有限公司 2024-08-06 CN disclosed
EP-4269119-A1 COLOR DEVELOPER, HEAT-SENSITIVE RECORDING MATERIAL, AND COATING MATERIAL FOR HEAT-SENSITIVE RECORDING LAYERS Sanko Co., Ltd. (JP) 2023-11-01 EP disclosed
EP-3856747-B1 SUBSTITUTED PYRIDOINDOLES FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION HOFFMANN LA ROCHE (CH) 2023-07-19 EP disclosed
EP-0679196-A1 DNA SEQUENCING BY MASS SPECTROMETRY SEQUENOM, INC. (US) 1995-11-02 EP disclosed
WO-1994021822-A1 DNA SEQUENCING BY MASS SPECTROMETRY VIA EXONUCLEASE DEGRADATION SEQUENOM, INC. (US) 1994-09-29 WO disclosed
WO-1994016101-A2 DNA SEQUENCING BY MASS SPECTROMETRY KOESTER HUBERT (US) 1994-07-21 WO disclosed
US-5045478-A Vesicles and use thereof in an assay BECTON DICKINSON AND COMPANY (US) 1991-09-03 US disclosed
EP-0147211-B1 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION SYNTEX (U.S.A.) INC. (US) 1990-09-12 EP disclosed
US-4828982-A Vesticles and use thereof in an enzyme assay BECTON, DICKINSON & COMPANY (US) 1989-05-09 US disclosed
US-4717676-A Vesicles and use thereof in an assay BECTON DICKINSON AND COMPANY (US) 1988-01-05 US disclosed
US-4657893-A ANTIINFLAMMATORY AGENTS SYNTEX (U.S.A.) INC. (US) 1987-04-14 US disclosed
EP-0147211-A2 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation SYNTEX (U.S.A.) INC. (US) 1985-07-03 EP disclosed