⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633356 | 0.72 | — | — | |
| SCHEMBL2796481 | 0.67 | — | — | |
| SCHEMBL4096257 | 0.67 | — | — | |
| SCHEMBL385743 | 0.64 | — | — | |
| SCHEMBL2054 | 0.61 | — | — | |
| SCHEMBL4072490 | 0.61 | — | — | |
| SCHEMBL264242 | 0.61 | — | — | |
| SCHEMBL2897 | 0.61 | — | — | |
| SCHEMBL3521050 | 0.61 | — | — | |
| SCHEMBL8728631 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117265889-A | High-flame-retardance high-ink-absorption quick-drying water-based canvas and preparation method thereof | 潍坊佳诚数码材料有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-113372072-B | 3D printing heat-preservation concrete containing SiO2 aerogel and preparation method thereof | 河北工业大学 | 2022-12-27 | — | — | CN | claimed |
| EP-0137456-B1 | DERIVATIVES OF PYRIDINE, PYRAZINE AND PYRIMIDINE AND THEIR USE AS FUNGICIDAL AGENTS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-02-10 | — | — | EP | claimed |
| CN-117954780-A | Separator for lithium battery and method for manufacturing same | 南亚塑胶工业股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117265889-A | High-flame-retardance high-ink-absorption quick-drying water-based canvas and preparation method thereof | 潍坊佳诚数码材料有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-113372072-B | 3D printing heat-preservation concrete containing SiO2 aerogel and preparation method thereof | 河北工业大学 | 2022-12-27 | — | — | CN | disclosed |
| CN-113372072-A | SiO-containing material2Aerogel 3D printing heat-preservation concrete and preparation method thereof | 河北工业大学 | 2021-09-10 | — | — | CN | disclosed |
| WO-2018102885-A1 | MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS AND USES THEREOF | BIONOMICS LIMITED (AU) | 2018-06-14 | — | — | WO | disclosed |
| EP-3023423-B1 | 2 -AMINO-4 - (PYRIDIN- 2 -YL) - 5, 6 -DIHYDRO-4H- 1, 3 -OXAZINE DERIVATIVES AND THEIR USE AS BACE-1 AND/OR BACE - 2 INHIBITORS | NOVARTIS AG (CH) | 2017-05-31 | — | — | EP | disclosed |
| EP-3023423-A1 | 2 -AMINO-4 - (PYRIDIN- 2 -YL) - 5, 6 -DIHYDRO-4H- 1, 3 -OXAZINE DERIVATIVES AND THEIR USE AS BACE-1 AND/OR BACE - 2 INHIBITORS | Novartis AG (CH) | 2016-05-25 | — | — | EP | disclosed |
| US-9163011-B2 | Oxazine derivatives and their use in the treatment of disease | NOVARTIS AG (CH) | 2015-10-20 | — | — | US | disclosed |
| US-6242454-B1 | Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants | BERLEX LABORATORIES INC. | 2001-06-05 | — | — | US | disclosed |
| US-6166088-A | CONTROLLING THROMBOSIS | BERLEX LABORATORIES, INC. (US) | 2000-12-26 | — | — | US | disclosed |
| US-6071912-A | INHIBIT HUMAN FACTOR XA AND ARE THEREFORE USEFUL AS PHARMACOLOGICAL AGENTS FOR THE TREATMENT OF DISEASE-STATES CHARACTERIZED BY THROMBOTIC ACTIVITY; AMINO-, OXY- AND THIA-SUBSTITUTED TRIAZINES | BERLEX LABORATORIES, INC. (US) | 2000-06-06 | — | — | US | disclosed |
| EP-0888271-A4 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LAB (US) | 2000-03-15 | — | — | EP | disclosed |
| US-5994375-A | ANTICOAGULANTS | BERLEX LABORATORIES, INC. (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0888271-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997029067-A1 | BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS | BERLEX LABORATORIES, INC. (DE) | 1997-08-14 | — | — | WO | disclosed |
| US-5622914-A | APPLYING A PYRAZOLYL OR IMIDAZOLYL QUINOLINE DERIVATIVE; PLANT DISEASE CONTROL | NIHON BAYER AGROCHEM K.K. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0703234-A1 | Microbicidal Quinoline Derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1996-03-27 | — | — | EP | disclosed |