⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2796481 | 0.67 | — | — | |
| SCHEMBL4096257 | 0.67 | — | — | |
| SCHEMBL8517727 | 0.65 | — | — | |
| SCHEMBL11546673 | 0.65 | — | — | |
| SCHEMBL8724964 | 0.64 | — | — | |
| SCHEMBL385743 | 0.64 | — | — | |
| SCHEMBL4072490 | 0.61 | — | — | |
| SCHEMBL2054 | 0.61 | — | — | |
| SCHEMBL2897 | 0.61 | — | — | |
| SCHEMBL387765 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609058-B1 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO CO (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0609058-A2 | Hexahydronaphthalene ester derivatives, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-08-03 | — | — | EP | disclosed |
| EP-0267432-B1 | ANTIBACTERIALLY ACTIVE PYRIDO-BENZOTHIAZINE DERIVATIVES WITH LONG TERM ACTION | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1991-12-27 | — | — | EP | disclosed |
| EP-0127883-B1 | (2-Imidazolin-2-yl)thieno and furo(2,3-b) and (3,2-b) pyridines and intermediates for the preparation thereof, and use of said compounds as herbicidal agents. | AMERICAN CYANAMID COMPANY (US) | 1989-06-07 | — | — | EP | disclosed |
| EP-0267432-A1 | Antibacterially active pyrido-benzothiazine derivatives with long term action | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1988-05-18 | — | — | EP | disclosed |
| US-4393217-A | ANXIOLYTICS, ANTIDEPRESSANTS | AMERICAN CYANAMID COMPANY (US) | 1983-07-12 | — | — | US | disclosed |
| US-4236005-A | ANTIANXIETY | AMERICAN CYANAMID COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4209621-A | TRANQUILIZERS | AMERICAN CYANAMID COMPANY (US) | 1980-06-24 | — | — | US | disclosed |
| US-4178449-A | Pyrazolo[1,5-a]pyrimidines and imidazo-[1,5-a]pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1979-12-11 | — | — | US | disclosed |