Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 15/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2246311 | 1.00 | MMP2 (0.43) | MMP2MMP1MMP8ACACBMAPT | |
| SCHEMBL2249037 | 0.93 | ACACB (0.44) | MMP2MMP1MMP8ACACBMAPT | |
| SCHEMBL2246852 | 0.91 | FAAH (0.44) | MMP2MMP1MMP8ACACBMAPT | |
| SCHEMBL5339496 | 0.90 | MMP2 (0.43) | MMP2MMP1MMP8ACACBMAPT | |
| SCHEMBL5339503 | 0.90 | MMP2 (0.43) | MMP2MMP1MMP8ACACBMAPT | |
| SCHEMBL2247431 | 0.90 | MMP2 (0.43) | MMP2MMP1MMP8ACACBMAPT | |
| SCHEMBL2250688 | 0.90 | MAPT (0.41) | ACACBMAPTALDH1A1ALOX15KMT2A | |
| SCHEMBL2245644 | 0.89 | ACACB (0.44) | MMP2MMP1MMP8ACACBMMP9 | |
| SCHEMBL2251429 | 0.88 | FAAH (0.42) | MMP2MMP1MMP8ACACBALDH1A1 | |
| SCHEMBL2250480 | 0.88 | MMP2 (0.42) | MMP2MMP1MMP8ACACBMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-B1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | SERONO LAB (CH) | 2009-04-29 | — | — | EP | claimed |