SCHEMBL3877680

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3874437	0.92	ALDH1A1 (0.35)	MAPTKDM4ENPSR1GAAATM
	SCHEMBL13255487	0.91	MAPT (0.40)	MAPTKDM4ENPSR1GAAATM
	SCHEMBL13255404	0.90	MAPT (0.42)	MAPTKDM4ENPSR1GAAATM
	SCHEMBL3867709	0.89	MAPT (0.43)	MAPTKDM4ENPSR1GAAALDH1A1
	SCHEMBL13255606	0.89	MAPT (0.39)	MAPTKDM4ENPSR1GAAATM
	SCHEMBL3868271	0.89	KDM4E (0.38)	MAPTKDM4EGAAALDH1A1MEN1
	Alcohol SCHEMBL3867585	0.89	MAPT (0.41)	MAPTKDM4ENPSR1GAAPDE4B
	SCHEMBL13255553	0.88	PDE3B (0.47)	MAPTKDM4ENPSR1GAAATM
	SCHEMBL3870135	0.88	MAPT (0.42)	MAPTKDM4ENPSR1GAAALDH1A1
	SCHEMBL3869489	0.88	MAPT (0.42)	MAPTKDM4ENPSR1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.