Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | C1S | P09871 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134312 | 0.89 | ALDH1A1 (0.52) | PRSS1PRSS2PRSS3KMT2ARECQL | |
| Cyanamide SCHEMBL7212151 | 0.87 | ALDH1A1 (0.52) | PRSS1PRSS2PRSS3KMT2ARECQL | |
| SCHEMBL8999045 | 0.78 | CES2 (0.50) | KMT2AALDH1A1POLBKDM4EGLA | |
| SCHEMBL9068811 | 0.77 | SMN1; SMN2 (0.43) | KMT2AALDH1A1HPGDMAPTL3MBTL1 | |
| SCHEMBL514730 | 0.77 | ALDH1A1 (0.46) | KMT2ARECQLALDH1A1PKMPOLB | |
| SCHEMBL9656417 | 0.76 | POLB (0.62) | PRSS1PRSS2PRSS3KMT2ARECQL | |
| SCHEMBL28161171 | 0.76 | POLB (0.48) | PRSS1PRSS2PRSS3KMT2ARECQL | |
| SCHEMBL26923546 | 0.76 | POLB (0.48) | PRSS1PRSS2PRSS3KMT2ARECQL | |
| SCHEMBL6127460 | 0.75 | KMT2A (0.48) | PRSS1PRSS2PRSS3KMT2ARECQL | |
| SCHEMBL11306314 | 0.75 | KMT2A (0.48) | PRSS1PRSS2PRSS3KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531112-B2 | Composition for forming dielectric, capacitor produced using composition, and printed circuit board provided with capacitor | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2009-05-12 | — | — | US | disclosed |
| US-20070027246-A1 | Composition for forming dielectric, capacitor produced using composition, and printed circuit board provided with capacitor | SAMSUNG ELECTRO-MECHANICS CO., LTD. (KR) | 2007-02-01 | — | — | US | disclosed |