Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 4/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5947594 | 0.77 | CYP1A2 (0.64) | CYP1A2CYP2D6CYP2C19CYP3A4ADRA1D | |
| SCHEMBL3878289 | 0.74 | CASR (0.57) | KDM4E | |
| SCHEMBL27614836 | 0.73 | CYP1A2 (0.52) | CYP1A2CYP2D6CYP2C19CYP3A4HDAC1 | |
| SCHEMBL3959544 | 0.73 | CYP1A2 (0.52) | CYP1A2CYP2D6CYP2C19CYP3A4HDAC1 | |
| SCHEMBL2538044 | 0.71 | CYP1A2 (0.62) | CYP1A2CYP2D6CYP2C19CYP3A4HDAC1 | |
| SCHEMBL7774786 | 0.71 | CHRM2 (0.81) | CYP1A2CYP2D6CYP2C19CYP3A4ADRA1D | |
| SCHEMBL5947672 | 0.71 | CYP1A2 (0.70) | CYP1A2CYP2D6CYP2C19CYP3A4ADRA1D | |
| SCHEMBL3963736 | 0.71 | CYP1A2 (0.55) | CYP1A2CYP2D6CYP2C19CYP3A4HDAC1 | |
| SCHEMBL27614794 | 0.70 | CYP1A2 (0.58) | CYP1A2CYP2D6CYP2C19CYP3A4ADRA1D | |
| SCHEMBL27614616 | 0.70 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C19CYP3A4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010150-A2 | STABLE EMULSION FORMULATIONS | Amgen Inc. (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007124465-A2 | STABLE EMULSION FORMULATIONS | AMGEN INC. (US) | 2007-11-01 | — | — | WO | claimed |
| EP-2037736-A1 | METHODS FOR TREATING CYSTIC KIDNEY DISEASES | Indiana University Research and Technology Corporation (US) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008008650-A1 | METHODS FOR TREATING CYSTIC KIDNEY DISEASES | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2008-01-17 | — | — | WO | disclosed |