Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5947672 | 0.91 | CYP1A2 (0.70) | CYP1A2CYP3A4CYP2D6CYP2C19ADRA1D | |
| SCHEMBL5947283 | 0.88 | BCHE (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19CHRM2 | |
| SCHEMBL5947135 | 0.87 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19CHRM2 | |
| SCHEMBL5947523 | 0.87 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19CHRM2 | |
| SCHEMBL5947296 | 0.85 | LTA4H (0.62) | NOS1NOS3NOS2BCHELTA4H | |
| SCHEMBL5947496 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2D6CYP2C19ADRA1D | |
| SCHEMBL5947093 | 0.84 | CYP1A2 (0.60) | CYP1A2CYP3A4CYP2D6CYP2C19ADRA1D | |
| SCHEMBL5947768 | 0.84 | KDM4E (0.59) | CYP1A2CYP3A4CYP2D6CYP2C19CHRM2 | |
| SCHEMBL5947462 | 0.84 | KDM4E (0.62) | CYP1A2CYP3A4CYP2D6CYP2C19CHRM2 | |
| SCHEMBL5947405 | 0.84 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2D6CYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060009511-A9 | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor | CHEN ZHAOGEN | 2006-01-12 | — | — | US | claimed |
| CN-1610547-A | N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor | LILLY CO ELI (US) | 2005-04-27 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060009511-A9 | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor | HTR6, HTR2C, HTR1B | CYP1A2 530/4885CYP3A4 939/4885CYP2D6 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.