Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2847183 | 0.89 | HTR2A (0.35) | — | |
| SCHEMBL3103739 | 0.85 | AKR1C3 (0.31) | — | |
| SCHEMBL3942531 | 0.84 | HTR6 (0.45) | HDAC10HDAC6 | |
| SCHEMBL2841737 | 0.84 | HTR6 (0.36) | — | |
| SCHEMBL2838884 | 0.82 | HTR2A (0.32) | — | |
| SCHEMBL15516198 | 0.76 | HTR2A (0.41) | — | |
| SCHEMBL3116935 | 0.76 | TFPI2 (0.34) | — | |
| SCHEMBL27736816 | 0.75 | AKR1C3 (0.36) | — | |
| SCHEMBL627039 | 0.67 | HTR2A (0.57) | — | |
| Hydrochloric Acid SCHEMBL8648129 | 0.66 | HTR2A (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116547-A1 | Substituted N-imidazo(2, 1-b) thiazole-5-sulfonamide derivatives as 5-TH6 ligands | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2009-11-11 | — | — | EP | claimed |