Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22732030 | 0.78 | TGM2 (0.55) | TGM2ALDH1A1MAPTLMNAPKM | |
| SCHEMBL10193855 | 0.76 | TGM2 (0.54) | TGM2ALDH1A1HTTGAA | |
| SCHEMBL23591753 | 0.75 | RXFP1 (0.51) | KDM4ETGM2MAPTLMNAGAA | |
| SCHEMBL24168417 | 0.74 | TLR8 (0.50) | KDM4ETGM2KDRTEK | |
| SCHEMBL30334853 | 0.74 | TLR8 (0.50) | KDM4ETGM2KDRTEK | |
| SCHEMBL5037103 | 0.74 | ALDH1A1 (0.68) | TGM2ALDH1A1MAPTLMNAPKM | |
| SCHEMBL16613920 | 0.73 | KDM4E (0.62) | KDM4EALDH1A1MAPTLMNAHTT | |
| SCHEMBL24168630 | 0.73 | TGM2 (0.49) | KDM4ETGM2ALDH1A1MAPTLMNA | |
| SCHEMBL24168411 | 0.73 | TEAD1 (0.74) | HTT | |
| SCHEMBL24168443 | 0.73 | TGM2 (0.43) | KDM4ETGM2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010507-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | ScheBo Biotech Aktiengesellschaft (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007110068-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | SCHEBO BIOTECH AG (DE) | 2007-10-04 | — | — | WO | disclosed |