Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658558 | 0.87 | ALDH1A1 (0.31) | ATM | |
| SCHEMBL28249684 | 0.78 | ALDH1A1 (0.47) | ATM | |
| SCHEMBL6086503 | 0.75 | ALDH1A1 (0.33) | — | |
| SCHEMBL3856433 | 0.68 | — | — | |
| SCHEMBL3855349 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL3873077 | 0.67 | — | — | |
| SCHEMBL5799756 | 0.66 | EGFR (0.33) | — | |
| SCHEMBL5799588 | 0.65 | PARP1 (0.33) | — | |
| SCHEMBL3252263 | 0.65 | PARP1 (0.33) | — | |
| SCHEMBL11113554 | 0.65 | ATM (0.49) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406250-B1 | INHIBITORS OF AKT ACTIVITY | MERCK SHARP & DOHME (US) | 2015-08-12 | — | — | EP | claimed |
| EP-2116547-A1 | Substituted N-imidazo(2, 1-b) thiazole-5-sulfonamide derivatives as 5-TH6 ligands | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2009-11-11 | — | — | EP | claimed |
| EP-2116547-A1 | Substituted N-imidazo(2, 1-b) thiazole-5-sulfonamide derivatives as 5-TH6 ligands | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2009-11-11 | — | — | EP | disclosed |