Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10851119 | 0.84 | ADORA3 (0.41) | ATMADORA3ARHSD11B1AKR1C3 | |
| SCHEMBL11106506 | 0.83 | RET (0.40) | ATMARALDH1A1POLBHTR7 | |
| SCHEMBL11109690 | 0.83 | ATM (0.37) | ATMALDH1A1HTR7HTR2B | |
| SCHEMBL11104414 | 0.83 | PPIA (0.38) | ATMALDH1A1POLBKMT2A | |
| SCHEMBL11105851 | 0.83 | AR (0.46) | ATMARALDH1A1POLBHTR7 | |
| SCHEMBL28249684 | 0.81 | ALDH1A1 (0.47) | ATMALDH1A1CYP2C9MEN1KMT2A | |
| SCHEMBL11107751 | 0.80 | PPIA (0.41) | ATMALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL11108838 | 0.80 | ALDH1A1 (0.47) | ATMARALDH1A1POLBMEN1 | |
| SCHEMBL11108787 | 0.80 | ALDH1A1 (0.44) | ATMARALDH1A1MEN1KMT2A | |
| SCHEMBL11113388 | 0.79 | CYP1A2 (0.51) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |