Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 3/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.47 |
| ▸ | CCND1 | P24385 | 3/20 | 0.47 |
| ▸ | CDK2 | P24941 | 3/20 | 0.47 |
| ▸ | CDK7 | P50613 | 3/20 | 0.47 |
| ▸ | CCNH | P51946 | 3/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | S100A9 | P06702 | 4/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888545 | 0.82 | PKM (0.44) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL1645094 | 0.79 | PKM (0.52) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL12560498 | 0.79 | PKM (0.52) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL2265194 | 0.79 | PKM (0.35) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL6038652 | 0.79 | PKM (0.52) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL4616033 | 0.79 | PKM (0.52) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL301846 | 0.79 | PKM (0.52) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL10590843 | 0.77 | CDK1 (0.41) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL5137127 | 0.77 | PKM (0.50) | PKMCDK1CCNB1CCNA2CCND1 | |
| SCHEMBL11757841 | 0.77 | PKM (0.50) | PKMCDK1CCNB1CCNA2CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| WO-2026102632-A1 | BETA-LACTAMASE INHIBITORS AND THEIR PREPARATION | HANSONSBECK INDUSTRIES LIMITED (CN) | 2026-05-21 | — | — | WO | disclosed |
| EP-4146651-B1 | SULFONYLAMIDINE SUBSTITUTED COMPOUNDS AND THEIR USE AS BETA-LACTAMASE INHIBITORS | NINGXIA ACADEMY AGRICULTURE & FORESTRY SCIENCES (CN) | 2026-03-04 | — | — | EP | disclosed |
| US-12410166-B2 | Sulfonylamidine substituted compounds and their use as beta-lactamase inhibitors | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2025-09-09 | — | — | US | disclosed |
| WO-2025075722-A1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS | FORMOSA PLASTICS CORPORATION, U.S.A. (US) | 2025-04-10 | — | — | WO | disclosed |
| US-20250115687-A1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS | FORMOSA PLASTICS CORP USA (US) | 2025-04-10 | — | — | US | disclosed |
| US-20250101143-A1 | CATALYST FOR OLEFIN POLYMERIZATION AND PRODUCTION METHOD FOR OLEFIN-BASED POLYMER | THE UNIVERSITY OF TOKYO (JP) | 2025-03-27 | — | — | US | disclosed |
| US-12247004-B2 | 2-amino-N-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use | Oxford Drug Design Limited (GB) | 2025-03-11 | — | — | US | disclosed |
| CN-114846000-B | 2-Amino-N- (amino-oxo-aryl-lambda 6-sulfinyl) acetamide compounds and therapeutic uses thereof | 牛津药物设计有限公司 | 2025-01-03 | — | — | CN | disclosed |
| EP-4442714-A1 | CATALYST FOR OLEFIN POLYMERIZATION AND PRODUCTION METHOD FOR OLEFIN-BASED POLYMER | The University of Tokyo (JP) | 2024-10-09 | — | — | EP | disclosed |
| US-5272128-A | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0511826-A2 | Phosphosulfonate herbicides | ROHM AND HAAS COMPANY (US) | 1992-11-04 | — | — | EP | disclosed |
| US-4997847-A | Thromboxane A2 antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (DE) | 1991-03-05 | — | — | US | disclosed |
| EP-0304271-A2 | Omega-arylsulphonamidoalkanoic acids for treatment of thromboxane medited diseases | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-02-22 | — | — | EP | disclosed |
| EP-0001113-B1 | THIENOTHIAZINE DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-11-11 | — | — | EP | disclosed |
| US-4180662-A | ANTIINFLAMMATORY, ANALGESIC, ANTIRHEUMATIC, ANTITHROMBOTIC | HOFFMANN-LA ROCHE INC. (US) | 1979-12-25 | — | — | US | disclosed |
| EP-0001113-A1 | Thienothiazine derivatives, their preparation and compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-03-21 | — | — | EP | disclosed |
| US-4075347-A | THIOPHENES | CHEVRON RESEARCH COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-3998961-A | Fungicidal sulfonamidothiophenes | CHEVRON RESEARCH COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
| US-3996243-A | Fungicidal 5-dialkylamino-4-nitrosulfonamidothiophenes | CHEVRON RESEARCH COMPANY (US) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12247004-B2 | 2-amino-N-(amino-oxo-aryl-lambda6-sulfanylidene)acetamide compounds and their therapeutic use | AARS1, ASNS, GARS1 | PKM 4165/4885CDK1 1524/4885CCNB1 2363/4885 |
| US-12410166-B2 | Sulfonylamidine substituted compounds and their use as beta-lactamase inhibitors | MGAM, MGAM2, ABCC1 | PKM 1397/4885CDK1 4513/4885CCNB1 4112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.