Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3992388 | 0.76 | TSHR (0.46) | GAASMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL3882170 | 0.74 | RXFP1 (0.52) | GAASMN1; SMN2KMT2ALMNAEPAS1 | |
| SCHEMBL6069585 | 0.70 | GAA (0.52) | GAASMN1; SMN2KMT2AEPAS1MAPK1 | |
| SCHEMBL3371729 | 0.70 | HPGD (0.58) | GAASMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL6069603 | 0.68 | ALDH1A1 (0.51) | GAASMN1; SMN2KMT2ALMNAMAPK1 | |
| SCHEMBL6707794 | 0.66 | GFER (0.65) | GAASMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL10435189 | 0.66 | SMN1; SMN2 (0.56) | GAASMN1; SMN2KMT2ALMNAMAPK1 | |
| SCHEMBL9861976 | 0.66 | MAPK1 (0.54) | GAASMN1; SMN2KMT2ALMNAMAPK1 | |
| SCHEMBL10435423 | 0.65 | ALDH1A1 (0.59) | GAASMN1; SMN2KMT2ALMNAMAPK1 | |
| SCHEMBL3368984 | 0.65 | CYP1A2 (0.57) | GAASMN1; SMN2KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010507-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | ScheBo Biotech Aktiengesellschaft (DE) | 2009-01-07 | — | — | EP | claimed |
| WO-2007110068-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | SCHEBO BIOTECH AG (DE) | 2007-10-04 | — | — | WO | claimed |
| EP-2010507-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | ScheBo Biotech Aktiengesellschaft (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007110068-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | SCHEBO BIOTECH AG (DE) | 2007-10-04 | — | — | WO | disclosed |