Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3992388 | 0.85 | TSHR (0.46) | RXFP1LMNAKMT2AFLT1KDR | |
| SCHEMBL3885508 | 0.79 | RAB9A (0.55) | RXFP1LMNAMAPTALDH1A1HTT | |
| SCHEMBL3880466 | 0.74 | GAA (0.54) | EPAS1LMNAKMT2AALDH1A1GAA | |
| SCHEMBL1808833 | 0.73 | CYP3A4 (0.54) | RXFP1KMT2ASMN1; SMN2 | |
| SCHEMBL16707356 | 0.72 | ADORA3 (0.52) | RXFP1LMNAPOLBMAPTKMT2A | |
| SCHEMBL6707794 | 0.71 | GFER (0.65) | LMNAKMT2AFLT1KDRALDH1A1 | |
| SCHEMBL8441802 | 0.71 | TLR7 (0.62) | MAPTKMT2AKDM4E | |
| SCHEMBL13734246 | 0.69 | GPBAR1 (0.61) | EPAS1LMNAPOLBMAPTKMT2A | |
| SCHEMBL11420447 | 0.69 | GPBAR1 (0.61) | EPAS1POLBMAPTKMT2AALDH1A1 | |
| SCHEMBL29059158 | 0.69 | EPAS1 (0.74) | RXFP1EPAS1LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010507-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | ScheBo Biotech Aktiengesellschaft (DE) | 2009-01-07 | — | — | EP | claimed |
| WO-2007110068-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | SCHEBO BIOTECH AG (DE) | 2007-10-04 | — | — | WO | claimed |
| EP-2010507-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | ScheBo Biotech Aktiengesellschaft (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007110068-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | SCHEBO BIOTECH AG (DE) | 2007-10-04 | — | — | WO | disclosed |