SCHEMBL3880674

SCHEMBL3880674

O=C1C=CC(C2CCCCC2)=CC1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
DAO P14920 2/20 0.33
HDAC4 P56524 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
CEL P19835 1/20 0.31
PTPRC P08575 1/20 0.30
PTPRF P10586 1/20 0.30
PTPN1 P18031 1/20 0.30
CDC25B P30305 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16874832 0.80 MAPT (0.39)
SCHEMBL7379814 0.73 THRB (0.31)
SCHEMBL20805298 0.65 CEL (0.30) CEL
SCHEMBL9104079 0.65
SCHEMBL7873844 0.64
SCHEMBL3696804 0.64 NR1I2 (0.30)
SCHEMBL7853927 0.62
SCHEMBL7844955 0.62
SCHEMBL7854073 0.62
SCHEMBL4531021 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101304982-B Process for the preparation of benzotriazepine derivatives JANSSEN PHARMACEUTICA NV 2013-03-13 CN claimed
CN-101304982-A Process for the preparation of benzotriazepine derivatives JANSSEN PHARMACEUTICA NV (BE) 2008-11-12 CN claimed
CN-112739755-B Expanded particles and expanded molded article 积水化成品工业株式会社 2023-02-17 CN disclosed
WO-2021112124-A1 HOT-MELT ADHESIVE AND FILTER ASSEMBLED USING SAID ADHESIVE 東亞合成株式会社 2021-06-10 WO disclosed
CN-112739755-A Expanded particles and expanded molded article 积水化成品工业株式会社 2021-04-30 CN disclosed
WO-2020195118-A1 RESIN COMPOSITION FOR PRODUCTION OF FOAM PARTICLES, FOAM PARTICLES, FOAM MOLDED BODY AND COMPOSITE STRUCTURE MEMBER 積水化成品工業株式会社 2020-10-01 WO disclosed
WO-2020065485-A1 EXPANDED PARTICLES AND EXPANDED MOLDED ARTICLE 積水化成品工業株式会社 2020-04-02 WO disclosed
CN-110785460-A Bead foam, resin composite provided with same, and method for producing bead foam 积水化成品工业株式会社 2020-02-11 CN disclosed
WO-2019189635-A1 EXPANDED BEADS, MOLDED FOAM, FIBER-REINFORCED COMPOSITE, AND AUTOMOTIVE COMPONENT 積水化成品工業株式会社 2019-10-03 WO disclosed
CN-101304982-B Process for the preparation of benzotriazepine derivatives JANSSEN PHARMACEUTICA NV 2013-03-13 CN disclosed
EP-2040101-A1 BASE FILM FOR PROTECTIVE FILM AND PROTECTIVE FILM COVERED POLARIZING PLATE Toyo Kohan Co., Ltd. (JP) 2009-03-25 EP disclosed
CN-101304982-A Process for the preparation of benzotriazepine derivatives JANSSEN PHARMACEUTICA NV (BE) 2008-11-12 CN disclosed
CN-101072787-A Substituted adenines and the use thereof ASTRAZENECA AB (SE) 2007-11-14 CN disclosed
CN-1835953-A 4-Cycloalkylaminopyrazolopyrimidine NMDA/NR2B antagonists MERCK & CO INC (US) 2006-09-20 CN disclosed
EP-1113704-A2 Diaphragm for a speaker unit JSP CORPORATION (JP) 2001-07-04 EP disclosed
EP-1090744-A2 Composite sheet having foamed polycarbonate resin layer and non-foamed polycarbonate resin layer JSP CORPORATION (JP) 2001-04-11 EP disclosed
EP-0482923-B1 Image transmitting transparent films and method for forming images using the same CANON KK (JP) 2001-01-31 EP disclosed
WO-2000042452-A1 LIGHT REFLECTOR JSP CORPORATION (JP) 2000-07-20 WO disclosed
US-5482760-A Light-transmitting film and method for forming images using the same CANON KABUSHIKI KAISHA (JP) 1996-01-09 US disclosed
EP-0482923-A1 Image transmitting transparent films and method for forming images using the same CANON KABUSHIKI KAISHA (JP) 1992-04-29 EP disclosed