Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883991 | 0.99 | APP (0.38) | FFAR4APPAKR1C3AKR1C2S1PR4 | |
| SCHEMBL3892987 | 0.93 | AKR1C3 (0.36) | AKR1C3AKR1C2S1PR4S1PR5PLA2G10 | |
| SCHEMBL3882740 | 0.90 | AKR1C3 (0.36) | AKR1C3AKR1C2S1PR4S1PR5MAPT | |
| SCHEMBL3882428 | 0.88 | AKR1C3 (0.35) | AKR1C3AKR1C2S1PR4S1PR5TACR1 | |
| SCHEMBL3883685 | 0.88 | AKR1C3 (0.36) | APPAKR1C3AKR1C2S1PR4S1PR5 | |
| SCHEMBL3882109 | 0.87 | PTGS2 (0.41) | APPPTGS2 | |
| SCHEMBL3884624 | 0.86 | PTGS2 (0.40) | APPPTGS2 | |
| SCHEMBL3882420 | 0.85 | APP (0.35) | FFAR4APP | |
| SCHEMBL3883960 | 0.85 | FFAR4 (0.39) | FFAR4APPAKR1C3AKR1C2S1PR4 | |
| SCHEMBL3896066 | 0.85 | FFAR4 (0.48) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |