Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.35 |
| ▸ | FABP4 | P15090 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880962 | 0.88 | FFAR4 (0.37) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 | |
| SCHEMBL3883991 | 0.87 | APP (0.38) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 | |
| SCHEMBL3893664 | 0.87 | PTGS2 (0.39) | FABP4THRATHRBAPPMCL1 | |
| SCHEMBL3897931 | 0.86 | CHRNA7 (0.36) | — | |
| SCHEMBL3882367 | 0.86 | FABP4 (0.44) | AKR1C3AKR1C2GPR88FABP4PTGER1 | |
| SCHEMBL3881060 | 0.86 | THRA (0.49) | FABP4THRATHRBMCL1BCL2A1 | |
| SCHEMBL3892394 | 0.86 | AKR1C3 (0.38) | AKR1C3AKR1C2GPR88FABP4PTGER1 | |
| SCHEMBL3885031 | 0.86 | MYC (0.42) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 | |
| SCHEMBL3883891 | 0.84 | XDH (0.39) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 | |
| SCHEMBL3882989 | 0.84 | AKR1C3 (0.38) | AKR1C3AKR1C2PTGER1PTGER4PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |