SCHEMBL388162

SCHEMBL388162

Cc1c(O)cc(C(C)(C)C)c(C)c1Cn1c(=O)n(Cc2c(C)c(O)cc(C(C)(C)C)c2C)c(=O)n(Cc2c(C)c(O)cc(C(C)(C)C)c2C)c1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 12/20 0.39
KDM4E B2RXH2 5/20 0.39
SMN1; SMN2 Q16637 5/20 0.39
ALOX15 P16050 5/20 0.39
MAPT P10636 4/20 0.39
CYP1A2 P05177 3/20 0.39
ATP2A2 P16615 1/20 0.39
ATP2A3 Q93084 1/20 0.39
TDP1 Q9NUW8 3/20 0.37
HIF1A Q16665 5/20 0.35
TP53 P04637 4/20 0.35
CYP2C9 P11712 4/20 0.35
CYP2C19 P33261 3/20 0.35
POLB P06746 2/20 0.32
TYR P14679 2/20 0.32
CA2 P00918 1/20 0.32
TSHR P16473 5/20 0.32
CYP3A4 P08684 4/20 0.32
MAPK1 P28482 3/20 0.32
KMT2A Q03164 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29171061 0.84 SMN1; SMN2 (0.34) ALDH1A1KDM4ESMN1; SMN2ALOX15MAPT
SCHEMBL26717 0.76 CYP2C19 (0.46) ALDH1A1KDM4ESMN1; SMN2ALOX15MAPT
SCHEMBL29353077 0.76 CYP2C19 (0.46) ALDH1A1KDM4ESMN1; SMN2ALOX15MAPT
SCHEMBL1434173 0.76 ALDH1A1 (0.39) ALDH1A1KDM4ESMN1; SMN2ALOX15MAPT
SCHEMBL17286821 0.75 TDP1 (0.54) ALDH1A1KDM4ESMN1; SMN2ALOX15MAPT
SCHEMBL29438281 0.74 HSPA5 (0.43) ALDH1A1KDM4ESMN1; SMN2MAPTCYP1A2
SCHEMBL6562169 0.74 HSPA5 (0.43) ALDH1A1KDM4ESMN1; SMN2MAPTCYP1A2
SCHEMBL98883 0.73 ALDH1A1 (0.52) ALDH1A1KDM4ESMN1; SMN2ALOX15MAPT
SCHEMBL14268294 0.73 CYP2C19 (0.43) ALDH1A1KDM4ESMN1; SMN2MAPTCYP1A2
SCHEMBL29042657 0.73 ALDH1A1 (0.39) ALDH1A1ALOX15MAPTTDP1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101547-B2 Transparent thermal recording medium OJI PAPER CO., LTD. (JP) 2012-01-24 US disclosed
EP-1918120-B1 TRANSPARENT THERMAL RECORDING MEDIUM OJI PAPER CO (JP) 2010-07-21 EP disclosed
US-20090227449-A1 Transparent Thermal Recording Medium OJI PAPER CO., LTD. (JP) 2009-09-10 US disclosed
EP-1918120-A1 TRANSPARENT THERMAL RECORDING MEDIUM Oji Paper Company Limited (JP) 2008-05-07 EP disclosed