Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242031 | 0.84 | P2RX7 (0.50) | P2RX7ACP3CNR2MC4RIDO1 | |
| SCHEMBL30705308 | 0.84 | P2RX7 (0.50) | P2RX7ACP3CNR2MC4RIDO1 | |
| SCHEMBL7011754 | 0.82 | ACP3 (0.49) | P2RX7ACP3CNR2IDO1TDO2 | |
| SCHEMBL10546400 | 0.81 | ACP3 (0.47) | P2RX7ACP3CNR2MC4RIDO1 | |
| SCHEMBL8911591 | 0.80 | P2RX7 (0.47) | P2RX7ACP3CNR2MC4RIDO1 | |
| SCHEMBL30062302 | 0.80 | P2RX7 (0.67) | P2RX7ACP3CNR2MC4RIDO1 | |
| SCHEMBL213827 | 0.80 | P2RX7 (0.67) | P2RX7ACP3CNR2MC4RIDO1 | |
| Ammonia Solution, Strong SCHEMBL27704288 | 0.78 | P2RX7 (0.65) | P2RX7ACP3CNR2MC4RIDO1 | |
| SCHEMBL21679847 | 0.77 | ACP3 (0.44) | P2RX7ACP3CNR2MC4RIDO1 | |
| SCHEMBL10540798 | 0.77 | ACP3 (0.44) | P2RX7ACP3CNR2MC4RIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980381-A | Substituted uracils and use thereof | 拜耳医药股份有限公司 | 2016-09-28 | — | — | CN | disclosed |
| WO-2009004430-A1 | N-BENZYL OXAZOLIDINONES AND RELATED HETEROCYCLEIC COMPOUNDS AS POTENTIATORS OF GLUTAMATE RECEPTORS | PFIZER INC. (US) | 2009-01-08 | — | — | WO | disclosed |