Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242031 | 1.00 | P2RX7 (0.50) | P2RX7ACP3CNR2ALDH1A1POLB | |
| SCHEMBL3881807 | 0.84 | P2RX7 (0.48) | P2RX7ACP3CNR2ALDH1A1POLB | |
| SCHEMBL30062302 | 0.82 | P2RX7 (0.67) | P2RX7ACP3CNR2ALDH1A1POLB | |
| SCHEMBL213827 | 0.82 | P2RX7 (0.67) | P2RX7ACP3CNR2ALDH1A1POLB | |
| SCHEMBL8911591 | 0.82 | P2RX7 (0.47) | P2RX7ACP3CNR2ALDH1A1POLB | |
| Ammonia Solution, Strong SCHEMBL27704288 | 0.80 | P2RX7 (0.65) | P2RX7ACP3CNR2ALDH1A1POLB | |
| SCHEMBL30705305 | 0.80 | P2RX7 (0.50) | P2RX7ACP3IDO1TDO2KIF11 | |
| SCHEMBL11758159 | 0.80 | P2RX7 (0.35) | P2RX7ALDH1A1 | |
| SCHEMBL7011754 | 0.79 | ACP3 (0.49) | P2RX7ACP3CNR2ALDH1A1POLB | |
| SCHEMBL700063 | 0.79 | P2RX7 (0.44) | P2RX7ACP3CNR2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041296-B | Aminoacetamides containing benzooxy alicyclic structures and uses thereof | 上海璃道医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |