SCHEMBL388197

SCHEMBL388197

CCCCCCCCCCSCCO

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
LMNA P02545 2/20 0.52
HSD17B10 Q99714 2/20 0.52
ALDH1A1 P00352 2/20 0.52
TSHR P16473 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
CES2 O00748 3/20 0.52
THRB P10828 2/20 0.52
GMNN O75496 1/20 0.52
TP53 P04637 1/20 0.52
POLB P06746 1/20 0.52
MAPT P10636 1/20 0.52
CYP2C9 P11712 1/20 0.52
BLM P54132 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.48
FAAH O00519 4/20 0.45
CES1 P23141 4/20 0.45
PLA2G6 O60733 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2908992 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR
SCHEMBL11014828 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR
SCHEMBL10929119 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR
SCHEMBL10914192 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR
SCHEMBL7671120 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR
SCHEMBL23015009 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR
SCHEMBL39035 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR
SCHEMBL4897794 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR
SCHEMBL10946456 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR
SCHEMBL39565 1.00 TDP1 (0.53) TDP1LMNAHSD17B10ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0152833-B1 NEW COPOLYMERIC POLYCONDENSATION PRODUCTS BETWEEN 1,10-BIS(2-HYDROXYETHYLTHIO)DECANE, POLY(OXYETHYLENEGLYCOL)S OR POLY(OXYPROPYLENEGLYCOL)S, AND BIS(CARBOXYLIC ACID)S NUOVO CONSORZIO SANITARIO NAZIONALE (IT) 1990-01-24 EP claimed
EP-0152824-B1 COMPOUNDS HAVING HYPOLIPEMIZING ACTIVITY NUOVO CONSORZIO SANITARIO NAZIONALE (IT) 1988-07-13 EP claimed
US-11053449-B2 Thioether-containing phenolic compounds THE LUBRIZOL CORPORATION (US) 2021-07-06 US disclosed
EP-3374478-B1 LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND LUBRIZOL CORP (US) 2021-01-06 EP disclosed
US-20200239805-A1 THIOETHER-CONTAINING PHENOLIC COMPOUNDS THE LUBRIZOL CORPORATION 2020-07-30 US disclosed
EP-3374478-A1 LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND The Lubrizol Corporation (US) 2018-09-19 EP disclosed
WO-2017083243-A1 LUBRICATING COMPOSITION COMPRISING THIOETHER-SUBSTITUTED PHENOLIC COMPOUND THE LUBRIZOL CORPORATION (US) 2017-05-18 WO disclosed
US-8859506-B2 Glycopeptide phosphonate derivatives THERAVANCE BIOPHARMA ANTIBIOTICS IP, LLC (US) 2014-10-14 US disclosed
US-20140024604-A1 GLYCOPEPTIDE PHOSPHONATE DERIVATIVES THERAVANCE, INC. (US) 2014-01-23 US disclosed
US-8541375-B2 Glycopeptide phosphonate derivatives THERAVANCE, INC. (US) 2013-09-24 US disclosed
US-20120283195-A1 GLYCOPEPTIDE PHOSPHONATE DERIVATIVES THERAVANCE, INC. (US) 2012-11-08 US disclosed
US-5593954-A MIXTURE OF BRINE, EMULSIFIER, AND AN OIL SOLUBLE COMPOUND THE LUBRIZOL CORPORATION (US) 1997-01-14 US disclosed
US-5593953-A THIOALKYL ETHERS THE LUBRIZOL CORPORATION (US) 1997-01-14 US disclosed
WO-1996034068-A1 FRICTION MODIFIER FOR WATER-BASED WELL DRILLING FLUIDS AND METHODS OF USING THE SAME THE LUBRIZOL CORPORATION (US) 1996-10-31 WO disclosed
WO-1996034069-A1 FRICTION MODIFIER FOR OIL-BASED (INVERT) WELL DRILLING FLUIDS AND METHODS OF USING THE SAME THE LUBRIZOL CORPORATION (US) 1996-10-31 WO disclosed
US-5561103-A CONTAINING SELF CONDENSATION PRODUCTS OF ALKYLTHIO ALKANOLS AND DISPERSANTS; LUBRICANTS THE LUBRIZOL CORPORATION (US) 1996-10-01 US disclosed
EP-0320939-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1993-06-09 EP disclosed
US-5187055-A Malondianilide coupler improved in fastness of color image produced FUJI PHOTO FILM CO., LTD. (JP) 1993-02-16 US disclosed
EP-0320939-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-06-21 EP disclosed
US-4031023-A Lubricating compositions and methods utilizing hydroxy thioethers THE LUBRIZOL CORPORATION (US) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140024604-A1 GLYCOPEPTIDE PHOSPHONATE DERIVATIVES PAG1, PGLS, PTMS TDP1 1773/4885LMNA 4271/4885HSD17B10 4088/4885
US-11053449-B2 Thioether-containing phenolic compounds TST, TH, COMT TDP1 694/4885LMNA 4850/4885HSD17B10 627/4885
US-20200239805-A1 THIOETHER-CONTAINING PHENOLIC COMPOUNDS TST, TH, COMT TDP1 694/4885LMNA 4850/4885HSD17B10 627/4885
US-20120283195-A1 GLYCOPEPTIDE PHOSPHONATE DERIVATIVES PAG1, PGLS, PTMS TDP1 1773/4885LMNA 4271/4885HSD17B10 4088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.