SCHEMBL3881973

SCHEMBL3881973

Cc1ccc(-c2cc(C)cc(C)c2P(=O)(O)O)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
TSHR P16473 1/20 0.39
PTPN5 P54829 1/20 0.36
GAA P10253 1/20 0.36
HDAC7 Q8WUI4 1/20 0.35
RAPGEF4 Q8WZA2 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
CSNK2A1 P68400 1/20 0.34
FDPS P14324 1/20 0.34
ESRRA P11474 1/20 0.34
PTK2B Q14289 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
MMP8 P22894 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11418617 0.91 LMNA (0.43) LMNATSHRPTPN5GAAHDAC7
SCHEMBL3887561 0.84 HDAC7 (0.47) LMNATSHRPTPN5HDAC7PTK2B
SCHEMBL3885256 0.82 HPRT1 (0.50) PTPN5HDAC7
SCHEMBL3893691 0.81 PTPN5 (0.44) TSHRPTPN5HDAC7CA12MMP8
SCHEMBL3883333 0.79 LMNA (0.43) LMNATSHRPTPN5GAAFDPS
SCHEMBL7821224 0.78 PGK1 (0.43) LMNATSHRGAARAPGEF4CA1
SCHEMBL3883447 0.77 BRD4 (0.37)
SCHEMBL3896492 0.73 HDAC7 (0.41) LMNATSHRHDAC7CA12CA1
SCHEMBL28667492 0.71 SRC (0.50) LMNATSHRPTPN5GAAHDAC7
SCHEMBL10110952 0.71 LMNA (0.44) LMNATSHRGAAHDAC7ESRRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed