SCHEMBL3881985

SCHEMBL3881985

Cc1cccc(CCOc2ccc(CCC(=O)O)cc2-c2ccc3[nH]ccc3c2)c1

nearest known ligand 0.51

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 7/20 0.51
FFAR1 O14842 11/20 0.45
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
LTB4R Q15722 1/20 0.43
ENPP2 Q13822 1/20 0.42
PPARG P37231 1/20 0.40
TP53 P04637 1/20 0.40
MDM2 Q00987 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3882044 0.93 FFAR4 (0.61) FFAR4FFAR1THRATHRBENPP2
SCHEMBL3882870 0.91 FFAR4 (0.45) FFAR4FFAR1THRATHRBLTB4R
SCHEMBL27607994 0.91 ENPP2 (0.48) FFAR4FFAR1LTB4RENPP2PPARG
SCHEMBL3884965 0.91 ENPP2 (0.41) FFAR4ENPP2
SCHEMBL3880827 0.89 FFAR1 (0.49) FFAR4FFAR1THRATHRBLTB4R
SCHEMBL3893365 0.87 PTGS2 (0.40) FFAR4FFAR1LTB4RENPP2PPARG
SCHEMBL3881410 0.87 FFAR4 (0.53) FFAR4FFAR1LTB4RENPP2
SCHEMBL3882776 0.86 FFAR1 (0.49) FFAR4FFAR1LTB4RENPP2PPARG
SCHEMBL3883503 0.86 S1PR1 (0.47) FFAR4FFAR1LTB4RENPP2TP53
SCHEMBL3883581 0.86 FFAR1 (0.45) FFAR4FFAR1THRATHRBLTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP claimed
US-6867320-B2 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2005-03-15 US claimed
EP-1477472-A1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2004-11-17 EP claimed
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2004-03-04 US claimed
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP disclosed
US-6867320-B2 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2005-03-15 US disclosed
EP-1477472-A1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2004-11-17 EP disclosed
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof PTGER1, CYSLTR1, PTGS1 FFAR4 115/4885FFAR1 13/4885THRA 1720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.