Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 8/20 | 0.40 |
| ▸ | YES1 | P07947 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3890246 | 0.99 | PTGER1 (0.40) | KEAP1NFE2L2SRCYES1PTGER1 | |
| SCHEMBL3888318 | 0.96 | PTGER1 (0.39) | KEAP1NFE2L2SRCYES1PTGER1 | |
| SCHEMBL3882409 | 0.90 | PTGER1 (0.42) | KEAP1NFE2L2SRCYES1PTGER1 | |
| SCHEMBL3883892 | 0.89 | SRC (0.40) | KEAP1NFE2L2SRCYES1PTGER1 | |
| SCHEMBL3884439 | 0.87 | C5AR1 (0.42) | KEAP1NFE2L2SRCYES1PTGER1 | |
| SCHEMBL3882520 | 0.87 | KEAP1 (0.38) | KEAP1NFE2L2SRCYES1PTGER1 | |
| SCHEMBL3894528 | 0.86 | BRD4 (0.46) | SRC | |
| SCHEMBL3884976 | 0.86 | PPARG (0.40) | KEAP1NFE2L2SRCYES1PTGER1 | |
| SCHEMBL3882380 | 0.86 | C5AR1 (0.38) | KEAP1NFE2L2SRCYES1PTGER1 | |
| SCHEMBL3894580 | 0.85 | C5AR1 (0.44) | KEAP1NFE2L2SRCYES1C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |