Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686308 | 0.90 | AR (0.41) | LIPGAPPARCCNCCDK8 | |
| SCHEMBL3880452 | 0.87 | THRA (0.44) | LIPGARCACNA1HDRD4SIGMAR1 | |
| SCHEMBL3889221 | 0.86 | THRA (0.46) | LIPGAPPARCACNA1HDRD4 | |
| SCHEMBL3888362 | 0.85 | ITGB1 (0.41) | LIPGARCACNA1HSIGMAR1TMEM97 | |
| SCHEMBL3897875 | 0.84 | ITGB1 (0.42) | LIPGAPPARCACNA1HCCNC | |
| SCHEMBL3882157 | 0.84 | CACNA1H (0.42) | LIPGARCACNA1HDRD4SIGMAR1 | |
| SCHEMBL3893294 | 0.83 | MAPK14 (0.41) | APPARCCNCCDK8PTGS1 | |
| SCHEMBL3885133 | 0.79 | FFAR4 (0.44) | LIPGCCNCCDK8CTSC | |
| SCHEMBL3682581 | 0.78 | THRA (0.46) | LIPGARSIGMAR1TMEM97FASN | |
| SCHEMBL3884457 | 0.77 | THRA (0.43) | APPCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |