Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
| ▸ | SGK2 | Q9HBY8 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881095 | 0.85 | THRA (0.47) | MAPK14TRPA1ROCK2ROCK1FFAR4 | |
| SCHEMBL3882443 | 0.85 | THRA (0.48) | MAPK14TRPA1ROCK2ROCK1CDK1 | |
| SCHEMBL3891048 | 0.85 | MAPK14 (0.41) | MAPK14TRPA1ROCK2ROCK1AURKA | |
| SCHEMBL3881923 | 0.84 | MAPK14 (0.40) | MAPK14TRPA1ROCK2ROCK1AURKA | |
| SCHEMBL3889253 | 0.84 | MAPK14 (0.40) | MAPK14TRPA1ROCK2ROCK1AURKA | |
| SCHEMBL3885580 | 0.83 | MAPK14 (0.42) | MAPK14TRPA1ROCK2ROCK1GSK3B | |
| SCHEMBL3882153 | 0.83 | LIPG (0.41) | APPPTGS1PTGS2ARCCNC | |
| SCHEMBL3888233 | 0.79 | TRPA1 (0.40) | MAPK14TRPA1ROCK2ROCK1AURKA | |
| SCHEMBL3883580 | 0.78 | BCL9 (0.40) | FGFR1AR | |
| SCHEMBL3884002 | 0.77 | F11 (0.40) | MAPK14TRPA1ROCK2ROCK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |