Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3882586 | 1.00 | FFAR4 (0.42) | FFAR4CCNCCDK8THRATHRB | |
| SCHEMBL3896066 | 0.92 | FFAR4 (0.48) | FFAR4CCNCCDK8THRATHRB | |
| SCHEMBL3883156 | 0.91 | CCNC (0.43) | FFAR4CCNCCDK8ALDH1A1LMNA | |
| SCHEMBL3883158 | 0.91 | CCNC (0.43) | FFAR4CCNCCDK8ALDH1A1LMNA | |
| SCHEMBL3884845 | 0.91 | THRA (0.49) | FFAR4CCNCCDK8THRATHRB | |
| SCHEMBL3885078 | 0.87 | FFAR4 (0.44) | FFAR4CCNCCDK8THRATHRB | |
| SCHEMBL3892987 | 0.87 | AKR1C3 (0.36) | — | |
| SCHEMBL3888801 | 0.86 | FFAR4 (0.41) | FFAR4CCNCCDK8THRATHRB | |
| SCHEMBL3888806 | 0.86 | FFAR4 (0.41) | FFAR4CCNCCDK8THRATHRB | |
| SCHEMBL3882504 | 0.85 | FFAR4 (0.45) | FFAR4CCNCCDK8THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |