Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 11/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896066 | 0.99 | FFAR4 (0.48) | THRATHRBFFAR4FFAR1CCNC | |
| SCHEMBL3882585 | 0.91 | FFAR4 (0.42) | THRATHRBFFAR4FFAR1CCNC | |
| SCHEMBL3882586 | 0.91 | FFAR4 (0.42) | THRATHRBFFAR4FFAR1CCNC | |
| SCHEMBL3887748 | 0.90 | CCNC (0.44) | THRATHRBFFAR4CCNCCDK8 | |
| SCHEMBL3675582 | 0.89 | CCNC (0.45) | THRATHRBFFAR4CCNCCDK8 | |
| SCHEMBL3885078 | 0.89 | FFAR4 (0.44) | THRATHRBFFAR4FFAR1CCNC | |
| SCHEMBL4008911 | 0.86 | THRA (0.47) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL4008909 | 0.86 | THRA (0.47) | THRATHRBFFAR4FFAR1 | |
| SCHEMBL3881060 | 0.86 | THRA (0.49) | THRATHRBFFAR4FFAR1CCNC | |
| SCHEMBL3883991 | 0.85 | APP (0.38) | FFAR4KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |