Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 3/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884668 | 0.91 | PTGS2 (0.42) | PTGS2CHRNA7XDHMTORENPP2 | |
| SCHEMBL3883278 | 0.86 | C5AR1 (0.41) | XDHKEAP1NFE2L2C5AR1 | |
| SCHEMBL3881187 | 0.86 | THRA (0.47) | CHRNA7XDHENPP2VCPACHE | |
| SCHEMBL3882037 | 0.85 | THRA (0.48) | CHRNA7XDHMTORENPP2VCP | |
| SCHEMBL3888457 | 0.84 | FFAR4 (0.42) | CHRNA7XDHENPP2VCPACHE | |
| SCHEMBL3884976 | 0.84 | PPARG (0.40) | XDHMTORVCPKEAP1NFE2L2 | |
| SCHEMBL3883830 | 0.84 | MEN1 (0.40) | CHRNA7MTORENPP2MAP3K11VCP | |
| SCHEMBL3882927 | 0.83 | PPARG (0.44) | PTGS2CHRNA7XDHMTORENPP2 | |
| SCHEMBL3883011 | 0.82 | HDAC1 (0.39) | CHRNA7MTORENPP2MAP3K11VCP | |
| SCHEMBL3882928 | 0.81 | CCNC (0.40) | CHRNA7XDHMTORENPP2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |