SCHEMBL3883095

SCHEMBL3883095

COc1ccc(F)cc1C(C)(C)CC1(C(F)(F)F)CO1.COc1ccc(F)cc1C(C)(C)CC1(C(F)(F)F)CO1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 10/20 0.47
NR3C1 P04150 19/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL303242 1.00 NR3C2 (0.47) NR3C2NR3C1
SCHEMBL4697278 1.00 NR3C2 (0.47) NR3C2NR3C1
SCHEMBL1774481 1.00 NR3C2 (0.47) NR3C2NR3C1
SCHEMBL4469875 0.86 NR3C1 (0.35) NR3C2NR3C1
SCHEMBL6251969 0.86 NR3C2 (0.42) NR3C2NR3C1
SCHEMBL12549422 0.85 NR3C2 (0.36) NR3C2NR3C1
SCHEMBL1716860 0.82 NR3C1 (0.40) NR3C2NR3C1
SCHEMBL1716861 0.82 NR3C1 (0.40) NR3C2NR3C1
SCHEMBL4474597 0.81 NR3C2 (0.44) NR3C2NR3C1
SCHEMBL14470146 0.80 IDO1 (0.33) NR3C2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2013185-A1 NOVEL COMPOUNDS Glaxo Group Limited (GB) 2009-01-14 EP disclosed
WO-2007122165-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2007-11-01 WO disclosed