Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 12/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 19/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774481 | 0.86 | NR3C2 (0.47) | NR3C2NR3C1 | |
| SCHEMBL4697278 | 0.86 | NR3C2 (0.47) | NR3C2NR3C1 | |
| SCHEMBL3883095 | 0.86 | NR3C2 (0.47) | NR3C2NR3C1 | |
| SCHEMBL303242 | 0.86 | NR3C2 (0.47) | NR3C2NR3C1 | |
| SCHEMBL6246602 | 0.81 | NR3C1 (0.39) | NR3C2NR3C1PGR | |
| SCHEMBL4469875 | 0.72 | NR3C1 (0.35) | NR3C2NR3C1 | |
| SCHEMBL4474597 | 0.72 | NR3C2 (0.44) | NR3C2NR3C1 | |
| SCHEMBL12549422 | 0.71 | NR3C2 (0.36) | NR3C2NR3C1PGR | |
| SCHEMBL1716860 | 0.69 | NR3C1 (0.40) | NR3C2NR3C1PGR | |
| SCHEMBL1716861 | 0.69 | NR3C1 (0.40) | NR3C2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583745-A1 | 1-PROPANOL AND 1-PROPYLAMINE DERIVATIVES AND THEIR USE AS GLUCOCORTICOID LIGANDS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004063163-A1 | 1-PROPANOL AND 1-PROPYLAMINE DERIVATIVES AND THEIR USE AS GLUCOCORTICOID LIGANDS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2004-07-29 | — | — | WO | disclosed |