Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3881435 | 0.93 | FAAH (0.47) | FAAH | |
| SCHEMBL15204325 | 0.92 | FAAH (0.41) | FAAHHSD11B1 | |
| SCHEMBL209241 | 0.87 | F10 (0.41) | HSD11B1 | |
| SCHEMBL15204253 | 0.85 | FAAH (0.44) | FAAHHSD11B1 | |
| SCHEMBL15204477 | 0.84 | FAAH (0.40) | FAAHHSD11B1 | |
| SCHEMBL3882100 | 0.84 | ERN1 (0.41) | HSD11B1 | |
| Trifluoroacetic Acid SCHEMBL3001621 | 0.83 | HDAC4 (0.40) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL3000850 | 0.83 | ERN1 (0.41) | HSD11B1 | |
| SCHEMBL15204166 | 0.82 | FAAH (0.42) | FAAHHSD11B1 | |
| SCHEMBL208631 | 0.80 | HSD11B1 (0.41) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016047-B1 | BIPHENYL AMIDE LACTAM DERIVATIVES AS INHIBITORS OF 11- BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2013-08-28 | — | — | EP | claimed |
| EP-1807072-B1 | CYCLOALKYL LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1 | LILLY CO ELI (US) | 2009-01-07 | — | — | EP | claimed |