Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884855 | 0.93 | GRM5 (0.32) | GRM5 | |
| SCHEMBL3880602 | 0.87 | GRM5 (0.37) | GRM5 | |
| SCHEMBL3882173 | 0.85 | PDE4B (0.39) | — | |
| SCHEMBL3878671 | 0.84 | CHRM4 (0.33) | GRM5 | |
| SCHEMBL5361447 | 0.83 | DGAT2 (0.38) | — | |
| SCHEMBL3878790 | 0.83 | EPHX2 (0.36) | GRM5 | |
| SCHEMBL3882076 | 0.82 | SMN1; SMN2 (0.36) | GRM5 | |
| SCHEMBL3879182 | 0.82 | FASN (0.39) | — | |
| SCHEMBL3882165 | 0.82 | GRM5 (0.43) | GRM5 | |
| SCHEMBL3879091 | 0.81 | UBE2M (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858900-B1 | FUSED THIAZOLE DERIVATIVES HAVING AFFINITY FOR THE HISTAMINE H3 RECEPTOR | GLAXO GROUP LTD (GB) | 2009-01-07 | — | — | EP | claimed |