Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3890174 | 0.92 | PTGER1 (0.53) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3884238 | 0.91 | PTGER1 (0.52) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3886278 | 0.91 | PTGER1 (0.45) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3885357 | 0.91 | PTGER1 (0.46) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3884031 | 0.91 | PTGS2 (0.42) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3891560 | 0.90 | PTGER1 (0.44) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3881961 | 0.90 | PTGER1 (0.41) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3885366 | 0.90 | PPARD (0.46) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3893638 | 0.89 | PTGER1 (0.43) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3886465 | 0.89 | PTGS2 (0.43) | PTGER1PTGER4PTGER3PTGER2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |