Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 2/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893638 | 0.92 | PTGER1 (0.43) | PPARDPPARAPTGER1PTGER4PTGER3 | |
| SCHEMBL3883264 | 0.90 | PTGER1 (0.46) | PPARDPPARAPTGER1PTGER4PTGER3 | |
| SCHEMBL3890174 | 0.90 | PTGER1 (0.53) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3886278 | 0.89 | PTGER1 (0.45) | S1PR1S1PR3S1PR5PTGER1PTGER4 | |
| SCHEMBL3884238 | 0.89 | PTGER1 (0.52) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3891560 | 0.88 | PTGER1 (0.44) | PPARAPTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3881440 | 0.87 | PTGS2 (0.40) | PPARDPPARAS1PR1S1PR3S1PR5 | |
| SCHEMBL3886347 | 0.87 | AKT1 (0.44) | PPARDPPARAS1PR1S1PR3S1PR5 | |
| SCHEMBL3884031 | 0.86 | PTGS2 (0.42) | PTGER1PTGER4PTGER3PTGER2PTGS2 | |
| SCHEMBL3884663 | 0.86 | FFAR1 (0.45) | PPARDPPARAS1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |