Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13687099 | 0.87 | MEN1 (0.51) | MEN1KMT2AOPRM1HSD11B1CHRM4 | |
| SCHEMBL8134575 | 0.83 | MEN1 (0.47) | MEN1KMT2AOPRM1HSD11B1CHRM4 | |
| SCHEMBL8133029 | 0.80 | SLC6A2 (0.48) | MEN1KMT2AOPRM1HSD11B1 | |
| SCHEMBL5476066 | 0.80 | KMT2A (0.48) | MEN1KMT2AC5AR1 | |
| SCHEMBL5476062 | 0.80 | KMT2A (0.48) | MEN1KMT2AC5AR1 | |
| SCHEMBL5476061 | 0.80 | KMT2A (0.48) | MEN1KMT2AC5AR1 | |
| SCHEMBL567000 | 0.79 | LMNA (0.48) | MEN1KMT2AOPRM1AGERMTNR1A | |
| SCHEMBL567001 | 0.79 | LMNA (0.48) | MEN1KMT2AOPRM1AGERMTNR1A | |
| SCHEMBL565751 | 0.79 | LMNA (0.48) | MEN1KMT2AOPRM1AGERMTNR1A | |
| SCHEMBL566999 | 0.79 | LMNA (0.48) | MEN1KMT2AOPRM1AGERMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7589207-B2 | Cyclohexyl compounds as CCR5 antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2009-09-15 | — | — | US | disclosed |
| EP-1569647-B1 | CYCLOHEXYL COMPOUNDS AS CCR5 ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2008-08-20 | — | — | EP | disclosed |
| US-20060122166-A1 | Cyclohexyl compounds as ccr5 antagonists | SMITHKLINE BEECHAM CORPORATION | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122166-A1 | Cyclohexyl compounds as ccr5 antagonists | CCR5, CCR1, CCR3 | MEN1 4748/4885KMT2A 4628/4885OPRM1 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.