SCHEMBL3883495

SCHEMBL3883495

CC(Cc1cc(N)c(OCCCc2ccccc2)c(-c2ccc3ccccc3c2)c1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 3/20 0.40
PLA2G2A P14555 3/20 0.40
PLA2G1B P04054 1/20 0.40
PLA2G5 P39877 1/20 0.40
PLA2G2C Q5R387 1/20 0.40
PLA2G12B Q9BX93 1/20 0.40
PLA2G12A Q9BZM1 1/20 0.40
PLA2G2F Q9BZM2 1/20 0.40
PLA2G3 Q9NZ20 1/20 0.40
PLA2G2E Q9NZK7 1/20 0.40
PLA2G2D Q9UNK4 1/20 0.40
AKR1C3 P42330 2/20 0.40
AKR1C2 P52895 2/20 0.40
PPARG P37231 3/20 0.39
PPARA Q07869 2/20 0.39
PPARD Q03181 1/20 0.39
CYSLTR2 Q9NS75 1/20 0.39
CYSLTR1 Q9Y271 1/20 0.39
PTGER1 P34995 1/20 0.38
PTGER4 P35408 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3882342 0.90 PPARG (0.39) PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C
SCHEMBL3885070 0.89 AKR1C3 (0.40) PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C
SCHEMBL3881788 0.87 PPARG (0.39) PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C
SCHEMBL3894677 0.86 AKR1C3 (0.43) PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C
SCHEMBL3896091 0.86 PPARG (0.42) PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C
SCHEMBL3886441 0.85 AKR1C3 (0.40) PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C
SCHEMBL3885151 0.85 PPARG (0.38) PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C
SCHEMBL3890767 0.85 FFAR1 (0.52) FFAR1
SCHEMBL3880893 0.83 FFAR1 (0.44) PLA2G10PLA2G2APLA2G1BPLA2G5PLA2G2C
SCHEMBL3889870 0.83 CCNC (0.48) FFAR1ALOX5MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP claimed