Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.39 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.39 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.39 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.39 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.39 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3883495 | 0.89 | PLA2G10 (0.40) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3882491 | 0.87 | THRA (0.53) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3882342 | 0.87 | PPARG (0.39) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3896091 | 0.87 | PPARG (0.42) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3886441 | 0.86 | AKR1C3 (0.40) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3894677 | 0.85 | AKR1C3 (0.43) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3883891 | 0.85 | XDH (0.39) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3880893 | 0.84 | FFAR1 (0.44) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3881788 | 0.84 | PPARG (0.39) | AKR1C3AKR1C2PPARGPPARDPPARA | |
| SCHEMBL3884827 | 0.83 | CCNC (0.48) | AKR1C3AKR1C2PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477472-B1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2009-01-14 | — | — | EP | claimed |